产品货号：
Z30122
中文名称：
ZC3H12A抗体
英文名称：
Anti-ZC3H12A Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ZC3H12A Antibody |
| 指标别名 | MCP induced protein 1;MCPIP;MCPIP1;Ribonuclease ZC3H12A;RP3 423B22.1;ZC3H12A |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB |
| 基因名称 | ZC3H12A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ZC3H12A antibody was raised against a 17 amino acid synthetic peptide near the center of human ZC3H12A.The immunogen is located within amino acids 330 - 380 of ZC3H12A. |
| 计算分子量 | 66kDa |
| 成分 | ZC3H12A Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ZC3H12A Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | ZC3H12A,also known as MCPIP,is an essential member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases.ZC3H12A has RNase activity that prevents some immune disorders by directly affecting the mRNA stability of interleukins such as IL-6 and IL12p40.Mice lacking the ZC3H12A gene suffered from severe anemia,and most dies within 12 weeks.Overexpression of ZC3H12A causes ER stress and induces a number of genes involved in apoptosis and autophagy,including JNK,PUMA,and beclin-1 in cardiac myoblasts,leading to cell death.ZC3H12A can also induce adipogenesis in 3T3-L1 pre-adipocytes in the absence of PPAPgamma,demonstrating the complex roles ZC3H12A plays. |
| Uniprot ID | Q5D1E8 |
| 基因名全称 | Zinc finger CCCH-type containing 12A |
| 蛋白名全称 | Zinc finger CCCH-type containing 12A |
| 推荐稀释比 | ZC3H12A antibody can be used for detection of ZC3H12A by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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